As of the census estimates of 2007, there were 25,953 people, 8,560 households, and 3,304 families residing in the city. The population density was 1,812.9 people per square mile (700.0/km²). There were 9,235 housing units at an average density of 737.6/sq mi (284.8/km²). The racial makeup of the city was 53% White, 39.4% African American, 0.1% Native American, 2.8% Asian,1.6% from other races, and 3% from two or more races. Hispanic or Latino of any race were 2.2% of the population.
There were 8,560 households out of which 17.9% had children under the age of 18 living with them, 21.9% were married couples living together, 13.5% had a female householder with no husband present, and 61.4% were non-families. 31.4% of all households were made up of individuals and 7.3% had someone living alone who was 65 years of age or older. The average household size was 2.27 and the average family size was 2.93.
In the city the population was spread out with 14.3% under the age of 18, 48.7% from 18 to 24, 16.6% from 25 to 44, 11.3% from 45 to 64, and 9.2% who were 65 years of age or older. The median age was 22 years. For every 100 females there were 88.6 males. For every 100 females age 18 and over, there were 87.3 males.
The median income for a household in the city was $19,016, and the median income for a family was $35,391. Males had a median income of $29,132 versus $20,718 for females. The per capita income for the city was $12,585. About 20.5% of families and 42.6% of the population were below the poverty line, including 33.9% of those under age 18 and 21.4% of those age 65 or over.
Interstate 16 is located 10 miles (16 km) to the south of Statesboro. Statesboro is also served by three U.S. highways: U.S. Highway 301, which runs north-south through the city, U.S. Highway 25, which runs northwest-south through the city, and U.S. Highway 80, which is the main east-west route through the city. The Veterans Memorial Parkway (Highway 301 Bypass and Highway 25 Bypass) forms a near circle around the city. Approximately three miles outside of Statesboro is the Statesboro-Bulloch County Airport, which can accommodate private aircraft but does not have a control tower or commercial flights. Most travelers choose to fly from the nearby Savannah-Hilton Head International Airport, which is located 45 miles (72 km) to the east and is served by nine commercial airlines. Statesboro is about three hours by highway from the major Hartsfield-Jackson Atlanta International Airport.