Henderson is one of the United States' fastest-growing cities, and currently ranks as the 73rd-largest.
According to the 2000 census, there were 175,381 people, 66,331 households, and 47,095 families residing in the city. The population density was 2,200.8 people per square mile (849.7/km²). There were 71,149 housing units at an average density of 892.8/sq mi (344.7/km²). The racial makeup of the city was 80.49% White, 3.76% African American, 0.70% Native American, 3.98% Asian, 0.42% Pacific Islander, 3.16% from other races, and 3.49% from two or more races. Hispanic or Latino of any race were 13.71% of the population.
There were 66,331 households out of which 33.0% had children under the age of 18 living with them, 56.4% were married couples living together, 10.0% had a female householder with no husband present, and 29.0% were non-families. 20.3% of all households were made up of individuals and 5.0% had someone living alone who was 65 years of age or older. The average household size was 2.63 and the average family size was 3.05.
In the city the population was spread out with 25.1% under the age of 18, 7.9% from 18 to 24, 32.5% from 25 to 44, 24.4% from 45 to 64, and 10.1% who were 65 years of age or older. The median age for the city was 36 years. For every 100 females there were 98.4 males. For every 100 females age 18 and over, there were 96.4 males.
The median income for a household in the city was $55,949, and the median income for a family was $61,176. The per capita income for the city was $26,815. About 3.9% of families and 5.6% of the population were below the poverty line, including 6.4% of those under age 18 and 4.7% of those age 65 or over.
The city is served by Citizens Area Transit (CAT) with its network of bus routes which run throughout the Las Vegas Valley.
Henderson is served by four major highways: Boulder Highway (State Route 582), which is the main thoroughfare connecting with Las Vegas and Boulder City; Lake Mead Parkway (State Route 564); Interstate 515 and Interstate 215. State Route 146, also known as Saint Rose Parkway, connects Interstate 15 near Sloan with Interstate 215 in Green Valley. This stretch is formerly a part of Lake Mead Parkway which is a direct link to Henderson for motorists traveling in and out of Southern California.
Henderson is home for the Henderson Executive Airport. The main airport for the metropolitan area is McCarran International Airport, located northwest of the city.
Street numbering is different within the city of Henderson than with the rest of the Las Vegas Valley. The center of Henderson lies within the intersection of Water Street and Lake Mead Parkway. The Henderson Police Department for years referred to Lake Mead Parkway (and its former name Lake Mead Drive) as "146", while Boulder Highway is often referred as "93", its former highway designation.
Henderson is linked with one railroad line, which is the Henderson spur of the Union Pacific Railroad. This line originally ended in Boulder City, but the southern terminus was later moved to near the vicinity of the "Interstate 215/Interstate 515 interchange".